LB1020 Scurvy: A forgotten illness?

Scurvy is classically thought to be a historical disease rarely found in developed countries, thanks increased awareness of the role ascorbic acid this disease. A non-verbal 19-year-old female with history developmental delay, G-tube (and by mouth intake), gumline bleeding, and poor dietary intake, presented bilateral lower extremity non-palpable petechial, perifollicular eruptions. She denied any significant pain, itch, or irritation from rash. Perifollicular petechiae scattered corkscrew hairs were on dermoscopy examination. suspicion her physical examination was confirmed serum levels vitamin C <0.1 mg/dL. Although, diagnosis clinical, histopathologic showed hyperkeratosis irregular acanthosis epidermis follicular spongiosis erythrocyte extravasation adjacent hair follicle consistent Scurvy. well-documented caused due deficiency Vitamin C, known cofactor enzymes involved synthesis collagen, carnitine catecholamines, gene expression maintenance. Thorough dermascopic will reveal symptoms such as hairs1 - some diagnostic clues lack functioning that occur Other collagen dysfunction include gingival ecchymosis, epistaxis, bone hemorrhage. In patients avoidant-restrictive food intake those renal imbalances are at risk acquiring Therefore, it important keep differentials presenting perform comprehensive exam, avoid misdiagnosis. 1. Hirschmann, J.V. G.J. Raugi, Adult scurvy. J Am Acad Dermatol, 1999. 41(6): p. 895-906; quiz 907-10. https://doi.org/ 10.1016/s0190-9622(99)70244-6.